Important Information About TOPROL-XL
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Toprol-XL dosage

Toprol-XL is available in 4 dosage strengths—25 mg, 50 mg, 100 mg, and 200 mg—with proven efficacy across all 4 doses.3

Reduction in SiDBP* and SiSBP with once-daily Toprol-XL3

TOPROL-XL Dosage Chart

Results from a US multicenter, randomized, double-blind, placebo-controlled, parallel-group, unbalanced factorial study. In part, it evaluated the antihypertensive efficacy and safety of once-daily dosing with extended-release metroprolol succinate monotherapy and placebo in adult patients with newly diagnosed or treated essential hypertension.3

Mean baseline SiDBP 100 mm Hg and mean baseline SiSBP 150 mm Hg

  • *SiDBP = sitting diastolic blood pressure.
  • SiSBP = sitting systolic blood pressure.
  • For each dose vs placebo.
  • In hypertension, initiate with 25 mg to 100 mg once daily. Increase at a weekly or longer interval to optimize clinical response. Dosages above 400 mg per day have not been studied1

Toprol-XL dosing options

Toprol-XL 25-mg tablet
White TOPROL-XL 25-mg tablet
Oval shape
Scored or notched on both sides
Engraved with A/ß on one side
Toprol-XL 50-mg tablet
White TOPROL-XL 50-mg tablet
Round shape
Scored or notched on one side
Engraved with A/mo on one side
Toprol-XL 100-mg tablet
White TOPROL-XL 100-mg tablet
Round shape
Scored or notched on both sides
Engraved with A/ms on one side
Toprol-XL 200-mg tablet
White TOPROL-XL 200-mg tablet
Oval shape
Scored or notched on both sides
Engraved with A/my on one side

Tablets shown larger than actual size.