If you've recently prescribed some of your hypertensive patients a twice-daily beta-blocker you may be interested in knowing that a once-daily option is available.
Once-daily Toprol-XL and its generic equivalent, metoprolol succinate, are indicated for the treatment of hypertension, alone or in combination with other antihypertensives.1
Toprol-XL and metoprolol succinate are available in extended-release tablets with oral administration, providing 24-hour hypertension treatment with 1 dose daily.1 TOPROL-XL maintained consistent plasma levels vs immediate-release metoprolol and immediate-release atenolol over 24 hours.2
Mean steady-state plasma concentrations2
Copyright © 1990 by The Journal of Clinical Pharmacology. Adapted by Permission of Sage Publications.
- Metoprolol is a beta1-selective (cardioselective) adrenergic-receptor-blocking agent, and at higher concentrations it also inhibits beta2-adrenoreceptors1